England, 1932. Dr Isla Fenwick has little interest in marriage, until a reunion with an old friend blossoms into to something more. But Isla is determined to fulfil a long-held promise to practice medicine in India. With her fiance's blessing she sails to Calcutta to set up a midwifery clinic - promising to return within the year.

There, Isla does her best to navigate a complex new world, and forms a deep connection with one of her colleagues - against all better instincts.

When a desperate rescue mission to save the one person who needs her the most takes her into the foothills of the Himalayas, Isla will be asked to pay the ultimate price for her passions.